Up to 1973 instruction in pharmacology was carried out by the Department of Pharmacology at the Faculty of Medicine at the Higher Institute of Medicine. In 1968 Prof. Tz. Stoichev, M.D., started a regular course on drug toxicology at the Department of Pharmaceutical and Organic Chemistry at the Faculty of Pharmacy. Later a practicum was added to the course.
In 1973 the Department of Pharmacology and Toxicology at the Faculty of Pharmacy was founded and headed by Prof. Dushka Staneva-Stoicheva, M.D., Ph.D.
In the years 1986-91 the department was part of the Department of Pharmacology at the Research Institute of Pharmacology and Pharmacy at the Medical Academy. Since 1991 this department has become a separate unit again, as a department at the Faculty of Pharmacy, with Prof. Dr. Margarita Karaivanova, D.Sc., as its head. Assoc. Prof. Nikolai Danchev, M.D., Ph.D., was elected in 2000 for head of the department.